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Showing 23 results

Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic

Author

Furnon, Wilhelm; Cowton, Vanessa M.; de Lorenzo, Giuditta; Orton, Richard J.; Herder, Vanessa; Cantoni, Diego; Ilia, Georgios; Correa Mendonca, Diogo; Kerr, Karen; Allan, Jay and 16 others

Source

Nature Microbiology

Type

Journal article

Published

03 January 2025
Mutational signature dynamics indicate SARS-CoV-2's evolutionary capacity is driven by host antiviral molecules

Author

Lamb, Kieran D.; Luka, Martha M.; Saathoff, Megan; Orton, Richard J.; Phan, My V.T.; Cotten, Matthew; Yuan, Ke; Robertson, David L.

Source

PLoS Computational Biology

Type

Journal article

Published

25 January 2024
SARS-CoV-2 in domestic UK cats from Alpha to Omicron: Swab surveillance and case reports

Author

Jones, Sarah; Tyson, Grace B.; Orton, Richard J.; Smollett, Katherine; Manna, Federica; Kwok, Kirsty T. T.; Suarez, Nicolas M.; Logan, Nicola; McDonald, Michael; Bowie, Andrea and 4 others

Source

Viruses

Type

Journal article

Published

19 August 2023
The P681H mutation in the spike glycoprotein of the alpha variant of SARS-CoV-2 escapes IFITM restriction and is necessary for type I interferon resistance

Author

Lista, Maria Jose; Winstone, Helena; Wilson, Harry; Dyer, Adam; Pickering, Suzanne; Galao, Rui Pedro; de Lorenzo, Giuditta; Cowton, Vanessa M.; Furnon, Wilhelm; Suarez, Nicolas M. and 7 others

Source

Journal of Virology

Type

Journal article

Published

09 November 2022
Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Author

Willett, Brian J.; Grove, Joe; MacLean, Oscar A.; Wilkie, Craig; de Lorenzo, Giuditta; Furnon, Wilhelm; Cantoni, Diego; Scott, Sam; Logan, Nicola; Ashraf, Shirin and 33 others

Source

Nature Microbiology

Type

Journal article

Published

16 September 2022
SARS-CoV-2 evolution and patient immunological history shape the breadth and potency of antibody-mediated immunity

Author

Manali, Maria; Bissett, Laura A.; Amat, Julien A.R.; Logan, Nicola; Scott, Sam; Hughes, Ellen C.; Harvey, William T.; Orton, Richard J.; Thomson, Emma C.; Gunson, Rory N. and 3 others

Source

Journal of Infectious Diseases

Type

Journal article

Published

03 August 2022
Adeno-associated virus 2 infection in children with non-A-E hepatitis

Author

Ho, Antonia; Orton, Richard J.; Tayler, Rachel; Asamaphan, Patawee; Tong, Lily; Smollett, Katherine; Davis, Christopher; Manali, Maria; McDonald, Sarah E.; Pollock, Louisa and 31 others

Source

medRxiv

Type

Journal article

Published

19 July 2022
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning

Author

Nickbakhsh, Sema; Hughes, Joseph; Christofidis, Nicolaos; Griffiths, Emily; Shabaan, Sharif; Enright, Jessica; Smollett, Katherine; Nomikou, Kyriaki; Palmalux, Natasha; Tong, Lily and 14 others

Source

Scientific Reports

Type

Journal article

Published

19 July 2022
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Author

Willett, Brian J.; Grove, Joe; MacLean, Oscar A.; Wilkie, Craig; de Lorenzo, Giuditta; Furnon, Wilhelm; Cantoni, Diego; Scott, Sam; Logan, Nicola; Ashraf, Shirin and 33 others

Source

Nature Microbiology

Type

Journal article

Published

07 July 2022
Selection analysis identifies clusters of unusual mutational changes in Omicron lineage BA.1 that likely impact Spike function

Author

Martin, Darren P.; Lytras, Spyros; Lucaci, Alexander G.; Maier, Wolfgang; Grüning, Björn; Shank, Stephen D.; Weaver, Steven; MacLean, Oscar A.; Orton, Richard J.; Lemey, Philippe and 28 others

Source

Molecular Biology and Evolution

Type

Journal article

Published

01 April 2022