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Showing 54 results

The SARS-CoV-2 Alpha variant caused increased clinical severity of disease in Scotland: a genomics-based prospective cohort analysis

Author

Pascall, David J.; Mollett, Guy; Vink, Elen; Shepherd, James G.; Williams, Thomas; Wastnedge, Elizabeth; Blacow, Rachel; Hughes, Joseph; Robertson, David L.; Lycett, Samantha J. and 24 others

Source

medRxiv

Type

Journal article

Published

21 February 2022
Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

Author

Aggarwal, Dinesh; Warne, Ben; Jahun, Aminu S.; Hamilton, William L.; Fieldman, Tom; du Plessis, Louis; Hill, Verity; Blane, Beth; Watkins, Emmeline; Wright, Elizabeth and 713 others

Source

Nature Communications

Type

Journal article

Published

08 February 2022
The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism

Author

Willett, Brian J.; Grove, Joe; MacLean, Oscar A.; Wilkie, Craig; Logan, Nicola; de Lorenzo, Giuditta; Furnon, Wilhelm; Scott, Sam; Manali, Maria; Szemiel, Agnieszka and 25 others

Source

medRxiv

Type

Journal article

Published

26 January 2022
Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection

Author

Dowell, Alexander C.; Butler, Megan S.; Jinks, Elizabeth; Tut, Gokhan; Lancaster, Tara; Sylla, Panagiota; Begum, Jusnara; Bruton, Rachel; Pearce, Hayden; Verma, Kriti and 34 others

Source

Nature Immunology

Type

Journal article

Published

01 January 2022
Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial

Author

Munro, Alasdair P.S.; Janani, Leila; Cornelius, Victoria; Aley, Parvinder K.; Babbage, Gavin; Baxter, David; Bula, Marcin; Cathie, Katrina; Chatterjee, Krishna; Dodd, Kate and 297 others

Source

Lancet

Type

Journal article

Published

18 December 2021
Genomic reconstruction of the SARS-CoV-2 epidemic in England

Author

Vöhringer, Harald S.; Sanderson, Theo; Sinnott, Matthew; de Maio, Nicola; Nguyen, Thuy; Goater, Richard; Schwach, Frank; Harrison, Ian; Hellewell, Joel; Ariani, Cristina V. and 923 others

Source

Nature

Type

Journal article

Published

16 December 2021
Efficacy and safety of COVID-19 vaccines in older people

Author

Soiza, Roy; Scicluna, Chiara; Thomson, Emma C.

Source

Age and Ageing

Type

Journal article

Published

02 December 2021
Reduced neutralisation of the Delta (B.1.617.2) SARS-CoV-2 variant of concern following vaccination

Author

Davis, Christopher; Logan, Nicola; Tyson, Grace B.; Orton, Richard J.; Harvey, William T.; Perkins, Jonathan S.; Mollett, Guy; Blacow, Rachel; Peacock, Thomas P.; Barclay, Wendy S. and 8 others

Source

PLoS Pathogens

Type

Journal article

Published

01 December 2021
The Alpha variant was not associated with excess nosocomial SARS-CoV-2 infection in a multi-centre UK hospital study

Author

Boshier, Florencia A.T.; Venturini, Cristina; Stirrup, Oliver; Guerra-Assunção, José Afonso; Alcolea-Medina, Adela; Beckett, Angela H.; Byott, Matthew; Charalampous, Themoula; da Silva Filipe, Ana; Frampton, Dan and 35 others

Source

Journal of Infection

Type

Journal article

Published

02 October 2021
SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study

Author

Stirrup, Oliver; Boshier, Florencia A.T.; Venturini, Cristina; Guerra-Assunção, José Afonso; Alcolea-Medina, Adela; Beckett, Angela H.; Charalampous, Themoula; da Silva Filipe, Ana; Glaysher, Sharon; Khan, Tabassum and 33 others

Source

BMJ Open Respiratory Research

Type

Journal article

Published

20 September 2021